Brain is a three-pound organ which controls all functions of the body. The surface of the cerebrum is called the cortex. It has a folded appearance with hills and valleys. The long-term memory is processed in the hippocampus region of the temporal lobe. Alzheimer's involves a major damage to the cerebral cortex and hippocampus region.
Magnetic resonance imaging (MRI), a type of brain scan, is an important part of the standard evaluation for Alzheimer's disease and for other forms of dementia. A radiologist compares the size and distributions of the bright and dark areas to determine whether a tissue is healthy or not.
The neurounal cell membrane contains amyloid precursor proteins (APP) and beta amyloid. APP is digested by several enzymes and gets accumulated in the extracellular space of the brain. This proteins gets aggreagated to form amyloid plaques which effects the neuronal and synaptic function, ultimately leading to neuronal death.