The pathophysiology of asthma is complex and involves airway inflammation, intermittent airflow obstruction, and bronchial hyperresponsiveness. Airway hyperresponsiveness or bronchial hyperreactivity is an exaggerated response to numerous exogenous and endogenous stimuli in asthma.
Family history is an important asthma risk factor. If you have a parent with asthma, you are three to six times more likely to develop the disease than someone who does not have a parent with it. Respiratory problems and certain allergies can also increase the risk.