What is rickets in children?
Rickets is a childhood disorder which involves softening and weakening of bones in children. In rickets, the bones are prone to fractures and deformity. The main reason of rickets is prolonged vitamin D deficiency. The function of vitamin D is to promote the absorption of calcium and phosphorus from. . . .+
Rickets is a condition that affects the development of bones in children. It affects the skeleton causing the bones to become weak and soft. Weak and soft bones lead to skeleton deformities and poor growth. Rickets is caused by a severe and prolonged deficiency of vitamin D.
Burosumab (KRN23) is a monoclonal IgG1 antibody that binds excess fibroblast growth factor 23. The FDA has approved it as the first treatment for a rare and inherited form of rickets called X linked hypophosphatemia.
Rickets is a problem in growing children in which the newly formed bone matrix does not mineralise properly. It indicates a deficiency of the bone constituents such as calcium, phosphate etc. Some children with hypocalcaemia (a condition characterized by calcium deficiency) are found to have rickets, but not all children with rickets will be hypocalcaemic.
The low level of calcium in your body is indicative of either deficiency of calcium or vitamin D or both, since vitamin D is necessary for absorption of calcium from your dietary sources. 99% of your body calcium is stored in teeth and bone as an in-house reservoir.
Many fruits are very good source of calcium. Some of them are listed here with serving size and their approximate calcium content. Dried fruits contain more calcium than fresh fruits. Nowadays, various milk substitutes are available with higher calcium content than cow’s milk such as almond milk, rice milk, and soy milk.
Severity and cause of rickets are region dependent. If a person with bone deformity is provided with proper nutrition, there are chances of him to recover. In severe cases, surgery is an option. Vitamin D and calcium deficiency should be fought with to avoid rickets.
Due to environmental factors and lack of nutrients such as vitamin D and calcium, rickets can develop in children. More of Asian and African countries are affected by it due to malnutrition but developed countries are also facing this problem due to insufficient nutrition and unhealthy lifestyle and/or reduced exposure to sunlight.